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Mark C Genovese Selected Research

Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)

12/2021Corrigendum to 'TNF-alpha inhibition for the treatment of cardiac sarcoidosis' seminars in arthritis and rheumatism. 2020 Jun;50(3):546-552.
7/2021Long-term safety and efficacy of olokizumab in patients with rheumatoid arthritis and inadequate response to tumor necrosis factor inhibitor therapy in phase II studies.
1/2020TNF-alpha inhibition for the treatment of cardiac sarcoidosis.
11/2018ABT-122, a Bispecific Dual Variable Domain Immunoglobulin Targeting Tumor Necrosis Factor and Interleukin-17A, in Patients With Rheumatoid Arthritis With an Inadequate Response to Methotrexate: A Randomized, Double-Blind Study.
11/2018Phase II Study of ABT-122, a Tumor Necrosis Factor- and Interleukin-17A-Targeted Dual Variable Domain Immunoglobulin, in Patients With Psoriatic Arthritis With an Inadequate Response to Methotrexate.
2/2016Safety and Efficacy of Open-label Subcutaneous Ixekizumab Treatment for 48 Weeks in a Phase II Study in Biologic-naive and TNF-IR Patients with Rheumatoid Arthritis.
11/2014A phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study of 2 dosing regimens of fostamatinib in patients with rheumatoid arthritis with an inadequate response to a tumor necrosis factor-α antagonist.
7/2014A phase II randomized study of subcutaneous ixekizumab, an anti-interleukin-17 monoclonal antibody, in rheumatoid arthritis patients who were naive to biologic agents or had an inadequate response to tumor necrosis factor inhibitors.
8/2012Longterm safety and efficacy of abatacept through 5 years of treatment in patients with rheumatoid arthritis and an inadequate response to tumor necrosis factor inhibitor therapy.
5/2011A 24-week, randomized, double-blind, placebo-controlled, parallel group study of the efficacy of oral SCIO-469, a p38 mitogen-activated protein kinase inhibitor, in patients with active rheumatoid arthritis.
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Mark C Genovese Research Topics

Disease

126Rheumatoid Arthritis
12/2023 - 03/2002
38Infections
01/2023 - 05/2004
14Necrosis
01/2021 - 06/2007
12Psoriatic Arthritis
11/2021 - 05/2007
10Neoplasms (Cancer)
06/2022 - 01/2003
8Herpes Zoster
01/2023 - 01/2017
8Arthritis (Polyarthritis)
12/2021 - 09/2005
7Pain (Aches)
11/2020 - 04/2013
7Fatigue
01/2019 - 04/2006
6Rheumatic Diseases (Rheumatism)
12/2021 - 01/2003
6Psoriasis (Pustulosis Palmaris et Plantaris)
11/2021 - 05/2007
6Synovitis
11/2020 - 02/2011
6Inflammation (Inflammations)
01/2020 - 05/2011
5Systemic Lupus Erythematosus (Libman-Sacks Disease)
08/2023 - 03/2002
5Osteitis
11/2020 - 04/2011
5Chronic Disease (Chronic Diseases)
01/2019 - 09/2006
4Injection Site Reaction
12/2020 - 05/2004
4Headache (Headaches)
04/2020 - 03/2012
4Neutropenia
01/2018 - 05/2004
3Sarcoidosis (Schaumann Disease)
07/2023 - 01/2020
3Respiratory Tract Infections (Respiratory Tract Infection)
04/2020 - 01/2018
3Autoimmune Diseases (Autoimmune Disease)
01/2009 - 03/2002
2Multiple Sclerosis
08/2023 - 01/2023
2Anemia
06/2022 - 04/2020
2Axial Spondyloarthritis
11/2021 - 12/2020
2Breakthrough Infections
10/2020 - 06/2020
2Opportunistic Infections (Opportunistic Infection)
10/2020 - 01/2019
2Granulomatous Mastitis
01/2020 - 07/2009
2Nasopharyngitis
01/2019 - 01/2018
2Hypersensitivity (Allergy)
11/2018 - 11/2018
2Urinary Tract Infections (Urinary Tract Infection)
01/2018 - 03/2012
2Hypertension (High Blood Pressure)
12/2015 - 06/2005
2Ankylosing Spondylitis
01/2014 - 06/2007
1Venous Thromboembolism
06/2022
1Cough
11/2020

Drug/Important Bio-Agent (IBA)

49Methotrexate (Mexate)FDA LinkGeneric
01/2021 - 06/2002
24Antirheumatic Agents (DMARD)IBA
06/2022 - 09/2005
19Adalimumab (Humira)FDA Link
01/2021 - 05/2007
16Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2021 - 09/2005
13baricitinibIBA
10/2020 - 02/2015
12Monoclonal AntibodiesIBA
07/2021 - 09/2008
11sarilumabIBA
07/2023 - 09/2014
11Etanercept (Enbrel)FDA Link
01/2020 - 06/2002
9Tumor Necrosis Factor InhibitorsIBA
11/2021 - 06/2010
9Abatacept (Orencia)FDA Link
01/2018 - 09/2005
8golimumabFDA Link
02/2016 - 06/2010
7GLPG0634IBA
01/2023 - 01/2019
7Janus Kinase InhibitorsIBA
01/2023 - 03/2012
6Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
07/2023 - 10/2008
6ixekizumabIBA
11/2021 - 07/2014
6Biomarkers (Surrogate Marker)IBA
11/2020 - 06/2005
6Biosimilar PharmaceuticalsIBA
11/2020 - 10/2017
6C-Reactive ProteinIBA
01/2019 - 10/2008
6tocilizumab (atlizumab)FDA Link
06/2017 - 10/2008
6ametantrone (HAQ)IBA
01/2017 - 09/2006
5Janus KinasesIBA
01/2023 - 01/2019
5Interleukin-17 (Interleukin 17)IBA
11/2018 - 01/2012
5LipidsIBA
01/2017 - 01/2014
5fostamatinibIBA
12/2015 - 02/2011
4CytokinesIBA
01/2021 - 06/2007
4Infliximab (Remicade)FDA Link
01/2020 - 06/2004
4upadacitinibIBA
11/2019 - 12/2016
4AntigensIBA
01/2016 - 09/2005
4Syk KinaseIBA
12/2014 - 09/2010
4AutoantibodiesIBA
01/2009 - 03/2002
3Interleukin-6 (Interleukin 6)IBA
07/2023 - 06/2007
3omega-Chloroacetophenone (Mace)IBA
01/2023 - 01/2019
3Agammaglobulinaemia Tyrosine KinaseIBA
01/2023 - 04/2020
3InterleukinsIBA
07/2021 - 06/2007
3FKB327IBA
11/2020 - 12/2019
3Transaminases (Aminotransferases)IBA
01/2017 - 09/2014
3tofacitinibIBA
05/2016 - 03/2012
3secukinumabIBA
01/2016 - 06/2013
3CreatinineIBA
01/2016 - 04/2002
3B-Cell Activating FactorIBA
08/2015 - 09/2013
3tabalumabIBA
08/2015 - 09/2013
3Rituximab (Mabthera)FDA Link
06/2010 - 09/2006
2evobrutinibIBA
08/2023 - 01/2023
2SteroidsIBA
07/2023 - 02/2011
2olokizumabIBA
07/2021 - 09/2014
2Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
11/2020 - 06/2007
2peficitinibIBA
12/2019 - 01/2017
2Creatine Kinase (Creatine Phosphokinase)IBA
11/2019 - 06/2007
2ABT-122IBA
11/2018 - 11/2018
2Janus Kinase 1IBA
01/2018 - 03/2016
2ChemokinesIBA
01/2018 - 06/2007
2Lipoproteins (Lipoprotein)IBA
01/2017 - 01/2016
22- ((2- (1H- pyrrolo(2,3- b)pyridin- 3- yl)pyrimidin- 4- yl)amino)- 2- methyl- N- (2,2,2- trifluoroethyl)butanamideIBA
11/2016 - 01/2016
2brodalumabIBA
02/2016 - 06/2014
2Phosphotransferases (Kinase)IBA
10/2015 - 10/2006
2Immunoglobulins (Immunoglobulin)IBA
08/2015 - 04/2002
2Interleukin-17 ReceptorsIBA
06/2014 - 01/2012
1salicylhydroxamic acid (SHAM)IBA
12/2023
1GlucocorticoidsIBA
07/2023
1poseltinibIBA
01/2021
1CC ChemokinesIBA
11/2020
1OtilimabIBA
11/2020

Therapy/Procedure

37Therapeutics
07/2023 - 06/2002
4Vagus Nerve Stimulation
12/2023 - 09/2020
2Biological Therapy
02/2011 - 06/2005